BIRC3 Polyclonal Antibody for Human(Homo sapiens) | EIAab.comBIRC3 Polyclonal Antibody for Human(Homo sapiens)

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Index > Protein center > BIRC3(Gene name) > Human

BIRC3 (Gene name),

Baculoviral IAP repeat-containing protein 3 (Protein name ), BIRC3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

BIRC3(API2;IAP1;MIHC;RNF49);

Protein name:

Baculoviral IAP repeat-containing protein 3;

Alternative:

C-IAP2;Apoptosis inhibitor 2(API2);Inhibitor of apoptosis protein 1(IAP-1;hIAP-1;hIAP1);IAP homolog C;TNFR2-TRAF-signaling complex protein 1;RING finger protein 49;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with SMAC and with PRSS25; these interactions inhibit apoptotic suppressor activity.

Function:

Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

604

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

604:

TFLS

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q13489

UniGene:

Hs.127799

Pfam:

PF00653

STRING:

9606.ENSP00000263464

MIM:

601721

SMR:

Q13489

KEGG:

hsa:330

Uniprot:

Q13489

FOR

ELISA Kit for Human Baculoviral IAP repeat-containing protein 3

Cat.:

E10855h

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96T

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ELISA Kit for Human Baculoviral IAP repeat-containing protein 3

Cat.:

E10855m

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96T

ELISA Kit for Human Baculoviral IAP repeat-containing protein 3

Cat.:

E10855d

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96T

CLIA Kit for Human Baculoviral IAP repeat-containing protein 3

Cat.:

U10855h

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96T

CLIA Kit for Human Baculoviral IAP repeat-containing protein 3

Cat.:

U10855m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Baculoviral IAP repeat-containing protein 3

Cat.:

U10855d

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96T

Polyclonal Antibody for Human Baculoviral IAP repeat-containing protein 3

Cat.:

P10855Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Baculoviral IAP repeat-containing protein 3

Cat.:

P10855Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Baculoviral IAP repeat-containing protein 3

Protein for Human Baculoviral IAP repeat-containing protein 3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"The TNFR2-TRAF signaling complex contains two novel proteins related to baculoviral inhibitor of apoptosis proteins."
Rothe M. , Pan M.-G. , Henzel W.J. , Ayres T.M. , Goeddel D.V.
Cell83:1243-1252(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes."
Liston P. , Roy N. , Tamai K. , Lefebvre C. , Baird S. , Cherton-Horvat G. , Farahani R. , McLean M. , Ikeda J. , Mackenzie A. , Korneluk R.G.
Nature379:349-353(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Liver.
3.

"Cloning and expression of apoptosis inhibitory protein homologs that function to inhibit apoptosis and/or bind tumor necrosis factor receptor-associated factors."
Uren A.G. , Pakusch M. , Hawkins C.J. , Puls K.L. , Vaux D.L.
Proc. Natl. Acad. Sci. U.S.A.93:4974-4978(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Fetal liver.
4.

"Vascular endothelial genes that are responsive to tumor necrosis factor-alpha in vitro are expressed in atherosclerotic lesions, including inhibitor of apoptosis protein-1, stannin, and two novel genes."
Horrevoets A.J.G. , Fontijn R.D. , van Zonneveld A.J. , de Vries C.J.M. , ten Cate J.W. , Pannekoek H.
Blood93:3418-3431(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

NIEHS SNPs program
Submitted (2004-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-260 AND LYS-401
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lymph.
7.

"Structure of the MLT gene and molecular characterization of the genomic breakpoint junctions in the t(11;18)(q21;q21) of marginal zone B-cell lymphomas of MALT type."
Baens M. , Steyls A. , Dierlamm J. , De Wolf-Peeters C. , Marynen P.
Genes Chromosomes Cancer29:281-291(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 362-441
8.

"cIAP1 Localizes to the nuclear compartment and modulates the cell cycle."
Samuel T. , Okada K. , Hyer M. , Welsh K. , Zapata J.M. , Reed J.C.
Cancer Res.65:210-218(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
9.

"IAPs: more than just inhibitors of apoptosis proteins."
Dubrez-Daloz L. , Dupoux A. , Cartier J.
Cell Cycle7:1036-1046(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
10.

"To fight or die - inhibitor of apoptosis proteins at the crossroad of innate immunity and death."
Lopez J. , Meier P.
Curr. Opin. Cell Biol.22:872-881(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
11.

"IAPs: from caspase inhibitors to modulators of NF-kappaB, inflammation and cancer."
Gyrd-Hansen M. , Meier P.
Nat. Rev. Cancer10:561-574(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
12.

"Inhibitor of apoptosis (IAP) proteins in regulation of inflammation and innate immunity."
Damgaard R.B. , Gyrd-Hansen M.
Discov. Med.11:221-231(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
13.

"The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2."
Mei Y. , Hahn A.A. , Hu S. , Yang X.
J. Biol. Chem.286:35380-35387(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION;INTERACTION WITH USP19
14.

"cIAP1/2 are direct E3 ligases conjugating diverse types of ubiquitin chains to receptor interacting proteins kinases 1 to 4 (RIP1-4)."
Bertrand M.J. , Lippens S. , Staes A. , Gilbert B. , Roelandt R. , De Medts J. , Gevaert K. , Declercq W. , Vandenabeele P.
PLoS ONE6:E22356-E22356(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN THE UBIQUITINATION OF RIPK1; RIPK2; RIPK3 AND RIPK4;INTERACTION WITH RIPK1; RIPK2; RIPK3 AND RIPK4
15.

"IAPs: guardians of RIPK1."
Darding M. , Meier P.
Cell Death Differ.19:58-66(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON FUNCTION
16.

"IKKepsilon-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex."
Zhou A.Y. , Shen R.R. , Kim E. , Lock Y.J. , Xu M. , Chen Z.J. , Hahn W.C.
Cell Rep.3:724-733(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN IKBKE UBIQUITINATION

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